Inhalation Toxicology of Fog Oil Obscurant. Phase I. Inhalation Exposure Facility

摘要

An inhalation exposure facility was developed, tested, and operated to expose rodents to a fog oil obscurant. The criteria considered in establishing the facility were: adequate chamber and exposure facility ventilation, control of chamber temperature, aerosol generation and control, aerosol monitoring, aerosol homogeneity, and aerosol removal. Conditioned air was supplied to the laboratory area through volume dampers controlled by thermostats providing individual air conditioning for each room. Room air was filtered before entering the chambers. Chamber temperature was monitored using a thermocouple and digital display thermometer and a control circuit provided chilled water to the chamber inlet air coil if the temperature was higher than desired. A manually adjusted blower pushed air through the inlet air coil, particulate and gas filters, and into a two-path generator/bypass loop.