Development of Paper, Chemical Agent Detector, 3-Way Liquid Containing Non-Mutagenic Dyes. 2. Replacement of the Blue Indicator Dye Ethyl-bis-(2,4-Dinitrophenyl Acetate (EDA)

摘要

As reported previously, two of the three dyes used in the Paper , Chemical Agent Detector, 3-Way Liquid have been found to be mutagenic. THis report describes the work leading to the replacement of the strongly mutagenic indicator dye EDA which is used in the paper to detect liquid droplets of V-type nerve agents. Candidates from several classes of indicator dyes were examined as possible replacements for EDA. These candidate dyes, either synthesized at DREO or obtained commercially, were taken through various stages of evaluation. The recommended replacement dye for EDA is 3', 3 , 5', 5 -tetrabromophenolphthalein ethyl ester (TBPE). Canada