Surveillance for Retrovirus Infections in Baboons (Papio anubis) from Two East African Countries. (Reannouncement with New Availability Information).

摘要

Immunosuppressive and lymphoproliferative disorders resembling acquired immunodeficiency syndrome (AIDS), lymphomas and leukemias of humans have been described for several non-human primates. While a number of different retroviruses have been linked to these disorders, further studies are warranted to define the significance of non-human primates as host of human retroviruses. Therefore, a preliminary serosurvey was conducted in an attempt to detect evidence of human retroviral infections in baboons (Papio anubis) captured in selected East African countries. Sera from 20 wild caught baboons, 17 from Kenya and 3 baboons from Djibouti, were assayed for HIV-1 reactivity using an ELISA (Abott) system, for HIV-2 using a micro elisa (Genetic Systems), and for HTLV-I activity using a microtiter particle agglutination test for detection of anti-HTLV-I/ATLA antibody (Serodia). In addition, aera from 3 Djiboutian baboons were analyzed by the Western Blot for evidence of HTLV-I infection.