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美国政府科技报告
>Synthesis of Ring Fluorinated Pyrazoles and Isoxazoles. The Effect of 2-Fluoro and 2-Chloro Substituents on the Keto-Enol Equilibria of 1,3-Diketones. (Final Report, May 25, 1988-May 18, 1990).
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Synthesis of Ring Fluorinated Pyrazoles and Isoxazoles. The Effect of 2-Fluoro and 2-Chloro Substituents on the Keto-Enol Equilibria of 1,3-Diketones. (Final Report, May 25, 1988-May 18, 1990).
To develop a synthesis of ring fluorinated heterocycles. A variety of pyrazoles and isoxazoles can now be prepared conveniently in one step, starting from their corresponding 2-fluoro-1,3-diketones, using ETOH as the solvent and an acid as the catalyst. The effect of fluorine and chlorine on the keto-enol equilibria of 1,3-diketones was also examined and rationalized on the basis of stereoelectronic effects. Fluoro-pyrazoles; Fluoro-isoxazoles; Organic compounds; 2-fluoro-1,3-diketones; Theses; ETOH; Keto-emolequilibria; Ethyl alcohol. (jg)
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