Optimal ECG Electrode Sites and Criteria for Detection of Asymptomatic Coronary

摘要

This report presents recent findings from the Selvester-Solomon forward model ofthe electrophysiology of the human heart simulating infarct and ischemia. This led to a study of a 16-lead ECG at the time of coronary angioplasty. Both the simulations and the angioplasty study (reported in detail in this report) provide evidence that routine screening of apparently healthy aircrews with Hi-Fi rest and exercise 30 lead ECGs will significantly improve the detection of asymptomatic coronary disease. Three ECG recording systems with signal processing of 30 simultaneous leads (30SL) have been developed. These systems record and store on disk up to 2 hr of continuous 3 lead rhythm strips and 10 s epochs of 30SL median beats sampled at 1 ms. Design documents, flow diagrams, schematics, and safety documentation for the 3 ECG mapping systems, and for 3 electrode locator systems designed and fabricated on this contract, are provided. The design of the study at Long Beach Memorial and Armstrong Laboratory is also presented for the follow-on 1 year's contract using 30SL data during exercise (and angioplasty) to define the optimal number of leads and criteria in them for the optimal detection of asymptomatic coronary disease in aircrew persons.