Application of Smooth Pursuit Eye Movement Analysis to Clinical Medicine.(Reannouncement with New Availability Information)

摘要

We analyzed pursuit tracking eye movements from selected neurological patientsand compared them to the responses of 20 normal subjects. The patients/subjects tracked a small spot of light moving sinusoidally in the horizontal plane at a frequency of 0.4 Hz and a peak-to-peak amplitude of 40 . The eye-movement responses were separated into a smooth-pursuit component and a saccadic component. We calculated the asymmetry as well as the gain and phase response of the smooth-pursuit component. The saccadic component was quantified by calculating the percentage of the total tracking movement contributed by the saccadic system. The patients with smooth-pursuit impairment exhibited a higher percentage of saccadic tracking and a lower smooth pursuit gain compared to the normal subjects. one patient with a unilateral lesion exhibited significant asymmetry in the smooth-pursuit component. In this case, the direction of the asymmetry indicated the side of the lesion. Eye movements, Smooth pursuit tracking, Ocular tracking saccades.