Severe skin toxicity observed with the combination of capecitabine and weekly paclitaxel in metastatic breast cancer patients.

摘要

BACKGROUND: Skin toxicity has recently been recognized as a dose-limiting toxicity of antineoplastic therapy. DISCUSSION: We report severe skin toxicity observed in anthracycline-pretreated metastatic breast cancer patients receiving the combination of capecitabine and weekly paclitaxel.