—Radioiodine long has been recommended as an effective, safe, and relatively simple means of treating feline hyperthyroidism. The use of a fixed dose entails the risk of overtreating many animals. —A simple method of estimating the dose of iodine-131 (~(131)I) was developed, based on the degree of clinical thyrotoxrcosis, the total serum level of thyroxrne, and goiter size. Fifty cats 9-19 years of age were studied. The great majority were domestic short-haired cats. Each factor was graded on a scale of 1 to 5, and the total score dictated whether ladioiodine was delivered in a dose of 120 MBq or less, 120-150 MBq, or 160 MBq or greater. Treatment was initially given intravenously and, later, subcutaneously.
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