Atrial fibrillation in cryptogenic stroke and TIA patients in The Nordic Atrial Fibrillation and Stroke (NOR-FIB) Study: Main results

摘要

Introduction: Secondary stroke prevention depends on proper identification of the underlying etiology and initiation of optimal treatment after the index event. The aim of the NOR-FIB study was to detect and quantify underlying atrial fibrillation (AF) in patients with cryptogenic stroke (CS) or transient ischaemic attack (TIA) using insertable cardiac monitor (ICM), to optimise secondary prevention, and to test the feasibility of ICM usage for stroke physicians. Patients and methods: Prospective observational international multicenter real-life study of CS and TIA patients monitored for 12?months with ICM (Reveal LINQ) for AF detection. Results: ICM insertion was performed in 91.5 by stroke physicians, within median 9?days after index event. Paroxysmal AF was diagnosed in 74 out of 259 patients (28.6), detected early after ICM insertion (mean 48?±?52?days) in 86.5 of patients. AF patients were older (72.6 vs 62.2; p ?