Phenolic glucosides from Flacourtia indica

摘要

A new phenolic glucoside, (rel)-2-(4′,6′-dibenzoyl-β- glucopyranosyloxy)-7-(1?-hydroxy-2?-ethoxy-6?-acetyloxy-3- oxocyclohex-4-enoyl)-benzyl alcohol (Flacourticin) (1) and the known, 2-(4′,6′-dibenzoyl-β-glucopyranosyl)-5-hydroxy benzyl alcohol (4′-benzoylpoliothrysoside) (2) together with the new, (2E)-heptyl-3-(3,4-dihydroxyphenyl) acrylate (3), (+)-catechin (4) and sitosterol-β-D-glucoside were isolated from Flacourtia indica. Their structures were assigned on the basis of 1D, 2D-NMR and as well by analysis of the LC-ESIMS data. The isolated compounds (1-4) were evaluated for α,α-diphenyl-β-picrylhydrazyl (DPPH) radical scavenging activity, and 3 was found to be two-fold less potent, with an IC_(50) =12.01 μg/mL, compared to the positive control, Rutin, (IC_(50) = 5.83 μg/mL).