Knowing when to stop

摘要

Axon guidance is not just a matter of sending axons in the right direction- they must also terminate in the right place The vertebrate retinotectal system is an excellent model for studying this mechanism, and John Flanagan and colleagues have developed an ingenious new in vitro assay to investigate how ephrin signals regulate the termination of retinal ganglion cell (RGC) axon growth in the tectum.