首页> 外文期刊>Military Medicine: Official Journal of AMSUS, The Society of the Federal Health Agencies >Military chemical warfare agent human subjects testing: part 1--history of six-decades of military experiments with chemical warfare agents.
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Military chemical warfare agent human subjects testing: part 1--history of six-decades of military experiments with chemical warfare agents.

机译:军事化学战剂人类受试者测试:第1部分–使用化学战剂进行六十年军事实验的历史。

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摘要

Military chemical warfare agent testing from World War I to 1975 produced thousands of veterans with concerns of possible long-term health consequences. Clinical and research evaluation of potential long-term health effects has been difficult because the exposures occurred decades ago, the identity of troops exposed and exposure magnitudes are uncertain, and acute effects during experiments poorly documented. In contrast, a companion article describes the large amount of information available about the specific agents tested and their long-term health effects. This short history describes U.S. military chemical-agent experiments with human subjects and identifies tested agents. Finally, the demonstrated need to anticipate future health concerns from military personnel involved in such military testing suggests current and future military researchers should be required, by law and regulation, to fully record the identity of those exposed, relevant exposure magnitude, and complete medical information for all subjects. New study protocols and institutional review board approvals for research involving military personnel should reflect this need.
机译:从第一次世界大战到1975年的军事化学战剂测试产生了数以千计的退伍军人,他们担心可能会对长期健康产生影响。临床和研究评估潜在的长期健康影响一直很困难,因为暴露发生在几十年前,暴露的部队身份和暴露程度尚不确定,并且实验期间的急性影响文献很少。相反,一篇附带的文章描述了有关所测试的特定药剂及其长期健康影响的大量信息。这段简短的历史描述了对人类受试者进行的美国军事化学制剂实验,并确定了经过测试的制剂。最后,事实证明需要预料参与这种军事测试的军事人员对未来健康的担忧,这表明法律和法规应要求当前和将来的军事研究人员完整记录被暴露者的身份,相关暴露程度以及完整的医学信息。对于所有主题。新的研究方案和涉及军事人员的研究的机构审查委员会批准应反映这种需求。

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