Proteomic analysis of endometrium in fertile women during the prereceptive and receptive phases after luteinizing hormone surge.

摘要

In fertile women the patterns of proteome during the prereceptive (day 2 after LH surge) and receptive (day 7 after LH surge) phases were analyzed by two-dimensional fluorescence difference gel electrophoresis and mass spectrometry. A total of 31 differentially expressed proteins (17 up-regulated and 14 down-regulated) were identified between the two phases, which is helpful in understanding the biological mechanisms underlying human endometrial receptivity.