Pharmacokinetics of tralokinumab in adolescents with asthma: implications for future dosing

Baverel Paul G.; Jain Meena; Stelmach Iwona; She Dewei; Agoram Balaji; Sandbach Sara; Piper Edward; Kuna Piotr

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Pharmacokinetics of tralokinumab in adolescents with asthma: implications for future dosing

机译：曲妥珠单抗在青少年哮喘中的药代动力学：对未来给药的影响

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来源
《British Journal of Clinical Pharmacology》 |2015年第6期|共13页
作者
Baverel Paul G.; Jain Meena; Stelmach Iwona; She Dewei; Agoram Balaji; Sandbach Sara; Piper Edward; Kuna Piotr;
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正文语种 eng
中图分类药理学;
关键词
Adolescent; Asthma; dosing; interleukin-13; population pharmacokinetic modelling; Tralokinumab;

机译：青少年;哮喘;给药;白介素-13;人群药代动力学模型;他洛酮单抗;

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1. Pharmacokinetics of tralokinumab in adolescents with asthma: implications for future dosing [J] . Baverel Paul G., Jain Meena, Stelmach Iwona, British Journal of Clinical Pharmacology . 2015,第6期

机译：曲妥珠单抗在青少年哮喘中的药代动力学：对未来给药的影响
2. Dose-Exposure-Response Relationship of the Investigational Anti-Interleukin-13 Monoclonal Antibody Tralokinumab in Patients With Severe, Uncontrolled Asthma [J] . Baverel Paul G., White Nicholas, Vicini Paolo, Clinical Pharmacology and Therapeutics . 2018,第5期

机译：调查 - 抗白细胞介素-13单克隆抗体ralokinumab在严重，不受控制的哮喘患者中的剂量曝光关系
3. A randomized, placebo-controlled, single ascending-dose study to assess the safety, tolerability, pharmacokinetics, and immunogenicity of subcutaneous tralokinumab in Japanese healthy volunteers [J] . Paul Baverel, Dewei She, Edward Piper, Drug metabolism and pharmacokinetics. . 2018,第3期

机译：一项随机，安慰剂对照，单次递增剂量的研究，旨在评估日本健康志愿者皮下注射曲妥单抗的安全性，耐受性，药代动力学和免疫原性
4. 7c Radiation dose and dose optimization in paediatric thorax examinations in HUCH Hospital for Children and Adolescents [C] . Parviainen T., Palmumaa R., Foehr A., Nordic Society for Radiation Protection ordinary meeting on radiation protection in the 2000s . 2003

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5. Prolonged alterations of cardiomyocyte gene expression following low dose high charge and energy particle radiation—implications for future deep space travel [D] . Schwab, John H., V 2015

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6. Pharmacokinetics of tralokinumab in adolescents with asthma: implications for future dosing [O] . Paul G. Baverel, Meena Jain, Iwona Stelmach, 2015

机译：曲妥珠单抗在青少年哮喘中的药代动力学：对未来给药的影响
7. Comment on “Effect of Age-Related Factors on the Pharmacokinetics of Lamotrigine and Potential Implications for Maintenance Dose Optimisation in Future Clinical Trials” [O] . Joseph F. Standing, Brian J. Anderson, Stefanie Hennig, 2018

机译：评述“年龄相关因素对乳草素的药代动力学以及未来临床试验中维持剂量优化的潜在影响”
8. A Physiologically-based Pharmacokinetic and Pharmacodynamic Model for the Oral Dosing of Rats with Ethyl Acrylate and Its Implications for Risk Assessment (paper Preprint) W-letter. [R] . 1992

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Pharmacokinetics of tralokinumab in adolescents with asthma: implications for future dosing

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