Diabetes may affect the expression of matrix metalloproteinases and their inhibitors more than smoking in chronic periodontitis

Bastos M. F.; Tucci M. A.; de Siqueira A.de Faveri M.Figueiredo L. C.Vallim P. C.Duarte P. M.

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Diabetes may affect the expression of matrix metalloproteinases and their inhibitors more than smoking in chronic periodontitis

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Background and ObjectiveNo previous study has directly compared the levels of matrix metalloproteinases (MMPs) and tissue inhibitor of metalloproteinases (TIMPs) between smokers and individuals with diabetes mellitus (DM) with periodontitis. Therefore, the aim of this study was to evaluate the gene expression of MMP-1, MMP-2, MMP-8, MMP-9, TIMP-1 and TIMP-2 in tissues with chronic periodontitis (ChP) of smokers and individuals with type 2 DM.

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来源
《Journal of periodontal research》 |2017年第2期|292-299|共8页
作者
Bastos M. F.; Tucci M. A.; de Siqueira A.de Faveri M.Figueiredo L. C.Vallim P. C.Duarte P. M.;
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作者单位

Univ Guarulhos, Dept Periodontol, Dent Res Div, Praca Tereza Cristina 229, BR-07023070 Guarulhos;

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原文格式 PDF
正文语种英语
中图分类口腔科学;
关键词
diabetes mellitus; metalloproteinase; periodontitis; smoking; tissue inhibitors of MMPs;

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1. Matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 expression and synthetic matrix metalloproteinase-2 inhibitor binding in ovarian carcinomas and tumor cell lines. [J] . Lalani el N, Foulkes WD, Boyce BTickle SCardillo MRBaker TPignatelli MStamp GW Laboratory investigation . 1996,第2期

机译：Matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 expression and synthetic matrix metalloproteinase-2 inhibitor binding in ovarian carcinomas and tumor cell lines.
2. Expression of Matrix Metalloproteinase-2 and -9 and Their Inhibitors in Peripheral Blood Cells of Patients with Chronic Hepatitis C [J] . Christian I. Haberkorn, Dirk Michels, Klaus H.W. BoekerMatthias BahrOmar HuegelPeer FlemmingRalf LichtinghagenThomas Seifert Clinical Chemistry . 2000,第2期

机译：Expression of Matrix Metalloproteinase-2 and -9 and Their Inhibitors in Peripheral Blood Cells of Patients with Chronic Hepatitis C
3. Immunolocalization of matrix metalloproteinases and TIMP‐1 (tissue inhibitor of metalloproteinases) in human gingival tissues from periodontitis patients [J] . M. C. Meikle, R. M. Hembry, J. HolleyC. HortonC. G. McFarlaneJ. J. Reynolds journal of periodontal research . 1994,第2期

机译：Immunolocalization of matrix metalloproteinases and TIMP‐1 (tissue inhibitor of metalloproteinases) in human gingival tissues from periodontitis patients
4. Plasma matrix metalloproteinase-9 level is better than serum matrix metalloproteinase-9 level to predict gastric cancer evolution [O] . Wu, C.Y., Wu, M.S., Chiang, E.P., 2014

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Diabetes may affect the expression of matrix metalloproteinases and their inhibitors more than smoking in chronic periodontitis

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