A previously characterized hypoxia microfluidic chip could be successfully evaluated and the Visisens system showed good sensing capabilities when compared to similar products. The biocompatibility and non-invasive operation mode of the sensor foils also enabled the determination of oxygen levels in microfluidic cell cultures and suggest suitable device materials (COC or PDMS) depending on the application and cell line of interest. Microfluidic devices equipped with oxygen sensing capabilities are promising candidates for drug screening studies and hypoxic cell culture applications.
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