Synthesis of 3'(β)-C-methyl Carbodine Analogues as Potential Anti-HCV Agents

摘要

The synthetic route of novel 3'-C-methyl carbodine analogue is described. The construction of tertiary alcohol at 3'-position of carbodine analogues was successfully made via sequential [3,3]-sigmatropic rearrangement, ring-closing metathesis (RCM) and stereoselective dihydroxylation reactions starting from ethyl glycolate.