Mass Spectrometry for Metabolomics

摘要

Metabolomics involves the comparison of metabolomes (the full metabolite complement of an organism) between control and test groups to find differences in their profiles. Those differences may be correlated to the disease being studied in biomarker discovery or to changes in metabolic output in toxicology studies when a drug candidate is introduced to a test subject. Environmental metabolomics is also growing in importance where studies are performed to assess chemical risks to wildlife and the environment or to monitor the maintenance of healthy livestock in intensive farming with respect to disease.