2-Aryl-7,7-Dimethyl-5,6,7,8-tetrahydrothieno3,2-cazepin-4-ones from 5,5-Dimethyl-1,3-cyclohexanedione

摘要

A novel synthesis of substituted thieno3,2-cazepinones is described. This new approach uses 5,5-di-methyl-1,3-cyclohexanedione (dimedone) as the starting material. Oxime intermediates are obtained in three steps from the aforementioned diketone. Using these intermediates, the title compounds are synthesized in moderate yields.