Thermal Decomposition of Some Cardiovascular Drugs (Telmisartane, Cilazapril and Terazosin HC.L)

摘要

Thermal analysis of some antihypertensive drugs, Telmisartan, Cilazapril and Terazosin HCL was achieved. Thermo-gravimetry, derivative thermogravimetry and differential thermal analysis were used through the work. Thermogravim-etric parameters such as activation energy, frequency factor and reaction order were calculated. The results show the stability value decrease in the order Telmisartan >Cilazapril >Terazosin. This method can be used in the quality control of pharmaceutical compounds because it is simple, fast and cheap.