Over 50 million people have epilepsy and the treatment gap between the developed world and the developing world is large, with more than 50% of people with active epilepsy in some countries receiving little or no treatment. Even in the developed world at least one third of individuals with epilepsy have seizures that cannot be fully controlled at all or without significant compromises to their quality of life. The challenge to improve seizure control for all people with epilepsy is great. The key will be the acquisition of new knowledge about epilepsy, including its mechanisms and consequences that can be translated into more effective management and to the reduction of the social stigma that continues to exist throughout the world, even in the 21st Century.
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