A young female with galactorrhoea and sudden onset chest pain.

摘要

A 27-year-old married woman presented to the gynaecology out-patient department with a 3 month history of galactorrhoea and irregular menstrual cycle. She also complained of polyuria and polydipsia. No history of visual problems could be elicited. After initial evaluation, she was referred to the endocrinology department for further investigation of her hormonal status. Clinical examination was essentially within normal limits except for the galactorrhoea. Her pertinent laboratory investigations included high serum prolactin level (150 ng ml ), low levels of gonadotropins (unde-tectable/ELISA), Cortisol (3.8 mug ml~(1)) and thyroid stimulating hormone (3.8 mug ml~(-1)), suggesting panhypopituitarism. A high resolution contrast enhanced MRI (CEMRI) of the sella was performed. MRI revealed a soft tissue mass in the suprasellar region involving hypothalamus, tuber cinerium and extending into,the pituitary stalk causing its expansion.