Plasma N-terminal pro-brain natriuretic peptide levels predict new-onset atrial fibrillation in patients with acute myocardial infarction

摘要

Atrial fibrillation is a commonly encountered arrhythmia in hospitalized acute myocardial infarction (AMI) patients, with a reported incidence ranging from 2 to 22% [1]. The adverse effects of AF in AMI patients were demonstrated in a recent meta-analysis [2]. A community-based cohort study indicated that AF is frequent in an AMI setting and was closely associated with both short-term mortality and major adverse cerebral and cardiovascular events (MACCE) during long-term follow-up [3]. Natriuretic peptide (NP) has been found to have a powerful predictive value for mortality, MACE and readmission in various cardiovascular diseases. Elevated brain natriuretic peptide (BNP) independently predicts new-onset AF in patients with ST-segment elevation myocardial infarction [4]. The aim of our study was to evaluate NT-proBNP as a predictor of new-onset AF in patients with AMI, regardless of the ST-segment elevation.