Hyperthermia classic commentary: 'Hyperthermia as an adjuvant to radiation therapy of recurrent or metastatic malignant melanoma. A multicentre randomized trial by the European Society for Hyperthermic Oncology' by J. Overgaard, D. Gonzalez Gonzalez, M.C.C.H. Hulshof, G. Arcangeli, O. Dahl, O. Mella & S.M. Bentzen, International Journal of Hyperthermia 1996;12:3-20.

摘要

Figure 1 presents one of the patients treated in Rotterdam last year. This then 76-year-old woman underwent excision of a small nodule on the tip of the nose in September 2007. Pathology showed basal cell carcinoma with adequate margins. There were wound-healing problems, however, and in January 20018 swelling and pain increased. New biopsies showed desmoplastic melanoma.Staging studies showed enlarged lymph nodes in both sides of the neck, and metastases in both lungs. She was therefore treated with palliative intent. According to the guidelines of the Dutch malignant melanoma working group, the treatment consisted of radiotherapy and hyperthermia.