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A three‐dimensional scar assessment tool for keloid scars: Volume, erythema and melanin quantified

机译:瘢痕疙瘩疤痕的三维疤痕评估工具:量化体积、红斑和黑色素

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Abstract Background There is no non‐invasive objective assessment tool to measure keloid scar characteristics over time. This study aimed to ascertain the ability of the Antera 3D? camera to detect differences in keloid features pre‐ and post‐steroid injection. In order to identify whether those variation could be considered as treatment response predicting factors. Methods Enrolled patients received three intra‐lesional steroid injections at four‐weekly intervals. Images were taken with the Antera 3D camera 12 and 24?weeks after treatment. Keloids’ colour, volume, and area as well as haemoglobin and melanin average levels and variation have been analysed pre‐ and post‐steroid injection. t Tests and relative risk have been used to analyse the significance and association strength of our finding. Results Forty patients have been enrolled in the study. Significant changes as been recorded in keloids’ volume and colour after steroid injection (P?
机译:摘要 背景 目前尚无非侵入性客观评估工具来测量瘢痕疙瘩疤痕随时间变化的特征。本研究旨在确定 Antera 3D 的能力?用于检测类固醇注射前后瘢痕疙瘩特征差异的相机。为了确定这些变异是否可以被视为治疗反应预测因素。方法 入组患者每4周接受3次病灶内类固醇注射。在治疗后 12 周和 24 周使用 Antera 3D 相机拍摄图像。瘢痕疙瘩的颜色、体积和面积以及血红蛋白和黑色素的平均水平和变化已经过类固醇注射前后的分析。t 检验和相对风险已被用于分析我们发现的意义和关联强度。结果 本研究共纳入40例患者。类固醇注射后瘢痕疙瘩的体积和颜色发生了显着变化(P?0.05)。53% 的患者记录了 Hb 降低,显示病理学没有复发,Hb 升高的患者显示早期复发。类固醇注射后黑色素变异显著(P?0.05),但未发现与治疗反应的相关性。结论 Antera 3D相机能够检测所研究的瘢痕疙瘩特征的差异,有助于通过两种方式:通过提供客观的纵向方法来监测和记录疤痕形态的变化,以及通过监测血红蛋白变化,这与治疗反应和复发可能性密切相关。允许临床医生确定哪些患者会及早做出反应,以便在必要时改变治疗方案,从而限制发病率和成本。

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