Papular Acrodermatitis of Childhood (Gianotti‐Crosti Disease)

摘要

Abstract:An 11‐year‐old boy had lentil‐sized lichenoid papules, localized to the limbs and trunk, together with acute, nonicteric, hepatitis B surface antigen‐positive hepatitis. The clinical picture and course were typical of Gianotti‐Crosti disease. Monoclonal antibodies were used to study the lymphocyte subpopulations and surface antigens in the inflammatory infiltrate in frozen sections of a skin biopsy specimen. The results provide data on the pathogenic mechanism of the papular