AbstractOrganisms routinely cultured from throat swabs and infectious agents of sepsis and/or meningitis were reviewed. During the last 12 years,Klebsiella pneumoniaeandEscherichia colihave been replaced byStaphylococcus aureusandPseudomonas aeruginosaas the predominant isolates from throat swabs after admission. These change in the etiologic pattern of infectious agents of sepsis and/or meningitis, i.e.,K. pneumoniae, E. coli, S. aureus, P. aeruginosaandstaphylococcus epidermidis, were in agreement with the organisms isolated from the throat swabs after admission. TheS. aureusisolated from throat swabs after admission showed a decrease in the bacterial activity of cloxacillin, cephazolin and cefotaxime since 1978.
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