Long‐Term Changes in the ERG Following Transection of the Optic Nerve in the Rabbit

摘要

AbstractThe changes in ERG were studied in the: rabbit for 22 months after transection of the optic nerve. Immediately after the transection a small amplitude increase was found. This increase was constant for the next 8 months. Twenty‐two months after the section, however, the amplitudes decreased. The initial increase is interpreted as a functional sign of the existence of Centrifugal activity in the optic nerve that decreases retinal excitability. The final decrease in the ERG amplitudes is interpreted as a sign of retrograde degeneration in the retin