Neurological Problems Arising in a Plant Manufacturing Tri-aryl Phosphates*

摘要

Three neurological cases are described whose clinical picture might cause problems in the differential diagnosis from that of tri-aryl phosphate poisoning.Case Iis a case of disseminated sclerosis,Case 2is one of primary muscular dystrophy andCase 3is that of a peripheral neuropathy associated with pernicious anaemia. In this last case consideration was given to the possibility that the low serum cholinesterase, initially present, might be specific to the neurological condition per se rather than to the associated anaemia. The difficulties encountered with neurological disorders occurring in a factory manufacturing tri-aryl phosphates, demonstrate that full clinical neurological examination is of paramount importance and that the estimation of cholinesterase level cannot be used as a substitute for such an examination