Comparative study of the association of human acrocentric chromosomes in male and female mitoses

摘要

This paper deals with a statistical study of the spatial relationships between the acrocentric chromosomes in men and in women as can be inferred from the analysis of metaphase figures. This analysis confirms the hypothesis that the acrocentric chromosomes are not randomly situated and shows as a new fact that this effect is considerably more striking in women than in men. This might account for a part of the prominent role attributed to the mother in many cases of mongolism.