Do older and younger patients derive similar survival benefits from novel oncology drugs? A systematic review and meta-analysis

摘要

Background: older patients are commonly believed to derive less benefit from cancer drugs, even if they fulfil clinical trial eligibility Talarico et al. (2004, J Clin Oncol, 22(22): 4626-31). We aim to examine if novel oncology drugs provide differential age-based treatment outcomes for patients on clinical trials.