In vivo release and retinal toxicity of cyclosporine-loaded intravitreal device

Paes de Almeida Felipe Piacentini; Saliba Juliana Barbosa; Santana Ribeiro Jefferson AugustoSiqueira Rubens CamargoFialho Silvia L.Silva-Cunha ArmandoJorge RodrigoMessias Andre

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In vivo release and retinal toxicity of cyclosporine-loaded intravitreal device

机译：In vivo release and retinal toxicity of cyclosporine-loaded intravitreal device

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摘要

To determine the in vivo release profile and retinal safety of cyclosporine A (CsA) delivered from a biodegradable poly-lactide-co-glycolide (PLGA) device in the vitreous cavity of rabbits' eyes.

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来源
《Documenta Ophthalmologica: Advances in Ophthalmology》 |2015年第3期|207-214|共8页
作者
Paes de Almeida Felipe Piacentini; Saliba Juliana Barbosa; Santana Ribeiro Jefferson AugustoSiqueira Rubens CamargoFialho Silvia L.Silva-Cunha ArmandoJorge RodrigoMessias Andre;
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作者单位

Univ Sao Paulo, Ribeirao Preto Sch Med, Dept Ophthalmol Otorhinolaryngol & Head & Neck Su, BR-14049;

Univ Fed Minas Gerais, Fac Pharm, Belo Horizonte, MG, Brazil;

Ezequiel Dias Fdn, Pharmaceut Res & Dev, Belo Horizonte, MG, Brazil;

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原文格式 PDF
正文语种英语
中图分类眼科学;
关键词
Rabbits; Electroretinography; Biodegradable implant; Intravitreal drug delivery; Cyclosporine; Retina; Toxicity;

In vivo release and retinal toxicity of cyclosporine-loaded intravitreal device

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