AbstractReserpine treatment of rats with a unilateral lesion of the nigro‐neostriatal dopamine neurons produced on the unoperated side a rigidity which could be demonstrated electromyographically in the calf muscles. There was also a more marked increase in thea‐and a decrease in the γ‐motoneuron excitability on the side contralateral than ipsilateral to the lesion indicating that the nigro‐neostriatal dopamine neurons influence muscle tone by causing a shift of the balance between the α‐ and γ‐moton
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