Thirty cases of obsession treated by point-stimulation and with small dose of chlorimipramine.

摘要

OBJECTIVE: To investigate the clinical therapeutic effects of point-stimulation for obsession. METHODS: Sixty cases of obsession were divided into two groups: a control group of 30 cases treated with chlorimipramine (Chl), and a treatment group of 30 cases treated by point-stimulation (PS) plus chlorimipramine (PS+Chl). The therapeutic effects and side-effect were evaluated according tb the criteria set in Yale-Brown Obsession Scale (Y-BOCS), Hamilton's depression scale (HAMD), brief psychiatric rating scale (BPRS) and treatment emergent symptom scale (TESS). RESULTS: The cure rate and markedly effective rate were respectively 26.7 and 56.6 in the control group, and 43.3 and 50 in the treatment group, suggesting that the therapeutic effect in the treatment group was better than that in the control group. The incidence of adverse side-effects was 73.33 in the control group and 46.67 in the treatment group, with a significant difference between the two groups (P<0.05). CONCLUSION: Point-stimulationplus small dose of chlorimipramine was superior to the simple chlorimipramine treatment, indicating that the combined method was more effective and safe for obsession with less side effects.