Disc deterioration and pain provocation in different low-back pain syndromes was studied using computed tomography (CT) discography. Data were prospectively collected for 300 patients (816 discs). Patients were classified by their pre-discography diagnosis of disc herniation (DH), degenerated disc (DD), lumbar syndrome (LS), lumbar radicular syndrome (LRS), or other. The CT/discograms were classified by discographic pain response, the amount of degeneration and annular disruption. Eighty-two percent of DH patients, 80percnt; of DD, 56percnt; of LS, and 59percnt; of LRS patients had both positive discographic pain provocation and moderate or severe disc deterioation. The study indicates that intradiscal pathology plays a major role in nonspecific low-back pain syndromes.
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