Evaluation of Safety and Efficacy of Clarina anti-acne face mask in the Treatment of Mild to Moderate Acne-Vulgaris:An Open Clinical Study

摘要

Acne vulgaris is a chronic inflammatory disease of the pilosebaceous follicle, characterised by comedones, papules, pustules, cysts, nodules and often scars in certain sites of predilection, namely, the face, neck, upper trunk and arms. The purpose of the study was to evaluate efficacy and safety of Clarina anti-acne face mask for the treatment of mild to moderate acne vulgaris. Ninety six subjects aged between 18 to 34 years suffering from mild to moderate acne vulgaris and who were willing to give informed written consent were included in the study. After obtaining informed consent, baseline history was obtained and all patients underwent a clinical examination and thorough skin examination. Patients were advised to apply Clarina anti-acne face mask evenly over cleansed face and neck avoiding the area around the eyes. Patients were instructed to allow the mask to dry for 10-15 minutes, remove with wet sponge and wash the skin with cool water. The response to therapy was evaluated at intervals of two weeks upto the six weeks by calculating the acne lesion score (ALS). During each follow-up visit, local skin examination was done and observations recorded in the structured case record sheet. Out of 96 patients, 27 patients presented with normal to dry skin, 12 patients with dry skin, 20 patients with normal'to oily skin and 37 patients with oily skin. Response to the treatment was observed at every two weeks interval. At the end of 6 weeks treatment, 8 patients showed excellent response, 22 patients showed a good response, 47 patients showed moderate response and 12 patients showed poor response.