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STABILITY STUDY OF TRIPHALA CHURNA

机译:三叶草的稳定性研究

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Triphala Churna is an Ayurvedic preparation, prepared by mechanical mixing of three fruit pericarp powders, Emblica officinalis Gaertn., Terminalia belerica Roxb. and Terminalia chebula Retz. It is sold in the market as over the counter drug and mainly used for constipation problems. The raw material was collected from the market, after confirming the appropriate time of collection, to get the fresh material. Triphala Churna was prepared as per the Ayurvedic Formulary of India, under the supervision of an Ayurvedic manufacturer. In the present study the stability of the preparation was studied as per ICH guidelines. The samples were incubated in stability chamber for accelerated studies (A) and long term studies (L). One set of samples was kept at ambient temperature and humidity for real time study (R). The samples were intermittently re-tested for organoleptic characters, physicochemical parameters and assay of the total tannins. It was observed that the results go along with the standard Ayurvedic text. The preparation has very short life when assessed on the basis of total tannins.
机译:Triphala Churna是一种印度草药制剂,是通过机械混合三种水果果皮粉末,Emblica officinalis Gaertn。,Terminalia belerica Roxb制成的。和Terminalia chebula Retz。它作为非处方药在市场上出售,主要用于便秘问题。在确认适当的收集时间之后,从市场上收集原材料,以获取新鲜材料。 Triphala Churna是根据印度阿育吠陀配方,在阿育吠陀制造商的监督下制备的。在本研究中,按照ICH指南研究了制剂的稳定性。将样品在稳定室中孵育以进行加速研究(A)和长期研究(L)。将一组样品保持在环境温度和湿度下进行实时研究(R)。间歇性地重新测试样品的感官特性,理化参数和总单宁含量的测定。据观察,结果与标准阿育吠陀文本一致。当基于单宁总量评估时,该制剂的寿命很短。

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