Mean platelet volume in diabetes mellitus

摘要

We measured mean platelet volume (MPV) in patients with diabetes mellitus, compared with MPV in non-diabetic control subjects. Mean MPV was significantly increased in the diabetic subjects (8.9±0.07 fL, mean±SEM) compared with nondiabetic subjects (8.0±0.05) (p<0.001). Since platelet size is a determinant of platelet function, with larger platelets being more reactive per unit volume, we believe platelets may play a part in the micro- and macro-vascular complications of diabetes mellit