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>The quinacrine fluorescence karyotype ofiMus musculus/iand demonstration of strain differences in secondary constrictions
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The quinacrine fluorescence karyotype ofiMus musculus/iand demonstration of strain differences in secondary constrictions
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机译:The quinacrine fluorescence karyotype ofiMus musculus/iand demonstration of strain differences in secondary constrictions
In the mouse, virtually every autosome pair, and the X and Y, was identified by its distinctive fluorescent banding pattern after staining with quinacrine mustard. The karyotype was characterized further by measurement of orcein-stained chromosomes and autoradiographic analysis of terminal DNA replication. The autoradiographic identification of the X and Y chromosomes was confirmed by this technique. Fluorescent karyotype analysis of inbred strains and a series of Fx hybrids involving C57BL/6J revealed a polymorphism, the presence or absence of a prominent secondary constriction on any of four different chromosomes, which was probably inherited in a simple Mendelian fashion.
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