The Effect of Mixture of Heavy Metals on Obesity in Individuals = 50 Years of Age

摘要

Little is known about the association between a mixture of heavy metals and obesity among individuals >= 50 years of age with comorbidities. Thus, we identified the associations of serum cadmium (Cd), lead (Pb), and mercury (Hg) with obesity using linear regression models; weighted quantile sum (WQS) regression, quantile g-computation (qgcomp), and Bayesian kernel machine regression (BKMR) were conducted as secondary analyses. Of the 6434 subjects included in the analysis, 13.8 had obesity and 44.6 had abdominal obesity. In the logistic regression model, serum Hg was associated with obesity and abdominal obesity, and significant trends were observed for these heavy metal tertiles (p = 50 years are required to determine the mixed effects of heavy metals on obesity and related diseases.