Among the emerging areas in health-care system, the implementation of Electronic Medical Record system and the discovery of Personalized Medicine are occupying top positions. While some of the personalized drugs have already been discovered, implementing this new medicare system requires a lot of changes in the traditional health-care system. This paper aims at identifying these critical changes required in the adoption of the Personalized Medicine system. A systemic attempt has been made to prepare a list of possible changes required for the adoption based on available literature. This research study shows that changes from reactive to efficient medical care, from trial and error to right treatment for right person at right time, from narrow mind-set to open mindedness, from open information of patients to secure information, from less emphasis on IT infrastructure to more emphasis on IT infrastructure are some of the significant changes that are necessary for implementing the revolutionary medicare system of personalized Medicine.
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