IT BECOMES MORE curious about other mice and more likely to socialize with them for long periods of time. It becomes less likely to glug massive amounts of alcohol. It wriggles, quavering, like a wet dog shaking off rain. And its head twitches, rapidly, side to side.Because a mouse on LSD cannot tell you that colors seem brighter or the walls are melting or a guitar solo somehow sounds purple, these head twitches are of tremendous importance to chemist Jason Wallach. "If you want to know if a compound is likely to cause a psychedelic effect in humans," says Wallach, speaking from his tiny office in the Discovery Center at Saint Joseph's University in Philadelphia, "you look to the mice, to that twitching."
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