The [1+1]-condensation reaction of natural castor oil (triglyceride of (R,Z)-(+)-12-hydroxy-9-octadecenoic acid) with malonic acid chloride was carried out by one-stage synthesis. Optically active macroheterocycles with four ester groups were obtained, their malonic fragment being additionally alkylaled by 1-bromotridecane or 2-(8-bromooctyl) tetrahydro-2H-pyran.
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