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机译:Body Surface Area Dosing of High-Dose Methotrexate Should Be Reconsidered, Particularly in Overweight, Adult Patients
Univ Paul Sabatier, Ctr Rech Cancerol Toulouse, CNRS ERL5294, INSERM UMR 1037, Toulouse, France;
Inst Univ Canc Toulouse Oncopole, Dept Hematol, Toulouse, France;
Ctr Hosp Univ Toulouse, Hop Rangueil, Ctr Reference Malad Renales Rares, Dept Nephrol &Inst Univ Canc Toulouse Oncopole, Inst Claudius Regaud, Lab Pharmacol, Toulouse, France;
high-dose methotrexate; therapeutic drug monitoring; acute kidney injury; body surface area; dose individualization;