SYNTHESIS AND PROPERTIES OF BIS(5-AMINO-1,3,4-THIADIAZOLE-2-YL)PROPANE AND ITS ACYLATED DERIVATIVE

摘要

This article is devoted to prediction of biological (including antibacterial) and cytotoxic properties and synthesis of binuclear heterocyclic amine - bis(5-amino-1,3,4-thiadiazole-2-yl)propane and its acylated derivative - bis(5-amino-(5'-N-acetylamino)-1,3,4-thiadiazole-2-yl)propane. The structures of obtained compounds were confirmed by data of IR, UV-Vis, NMR spectroscopy, mass-spectrometry and X-ray spectral microanalysis. The possibility to exhibit liquid crystal properties by the synthesized products was shown.