Pattern visual evoked potential and foveal sensitivity in amblyopia

摘要

Abstract Purpose Amblyopic eyes show impaired visual functions such as poor visual acuity and reduced foveal sensitivity. The purpose of this study was to determine the association between foveal threshold and visual evoked potentials (VEP) in strabismic and anisometropic amblyopia.Methods Forty-five subjects (age range: 7–28?years, 43.3% female) including 15 strabismic and 15 anisometropic amblyopes, and 15 age-similar control subjects?participated in this study. Each subject had pattern visual evoked potentials?and foveal threshold recorded in each eye using RetiScan (Roland Consult, Germany) and Humphrey Visual Field Analyzer II (HFA II; Carl Zeiss Meditec Inc., Dublin, CA), respectively. These outcomes were compared?among the amblyopic eyes, their fellow eyes, and the control eyes.Results Compared to the amblyopic eyes (Mean?±?SD: 33.4?±?3.48?dB), the foveal threshold was higher in fellow eyes (37.0?±?2.04?dB, p?=?0.0002) and in?control eyes (38.7?±?0.96?dB, p?