Chromosome regional mapping for the human thyroid stimulating hormone β subunit (TSHB) gene

摘要

The human thyroid stimulating hormone β subunit (TSHB) gene, located on chromosome 1, was studied to determine its subregional location by in situ hybridization and Southern blot analysis of human × mouse hybrid cells. The results allowed localization of TSHB to the proximal portion of lp22, which is in the region of localization of the linkage group including amylase (AMY), nerve growth factor β subunit (NGFB), and NRAS, which are conserved in humans and roden