A silaproline-containing dipeptide

摘要

The silaproline-containing dipeptide N-(3,3-dimethyl-1-pivaloyl-1-aza-3-sila-5-cyclopentylcarbonyl)-L-alanine isopropylamide, C17H33N3O3Si, has two independent molecules in the asymmetric unit and each adopts a beta -II folded conformation, where the amide on the terminal C interacts intramolecularly with the pivaloyl O atom. The five-membered silaproline ring is C-beta-puckered, an infrequent conformation for the homologous proline ring. References: 14