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Spontaneous resolution of focal eosinophilic myositis of the adductor pollicis complicated by lung lesions

机译:自发的解决焦嗜酸性内收肌的肌炎全身最复杂肺损伤

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Eosinophilic myositis is characterised by peripheral blood eosinophilia and eosinophilic infiltration in muscles, and is comprised three subtypes: focal eosinophilic myositis (FEM), eosinophilic polymyositis, and eosinophilic perimyositis. Muscle involvement of FEM is usually limited to the lower legs, and pulmonary complications have not been reported. We report a rare case of FEM in the left adductor pollicis complicated by lung lesions. A 37-year-old woman developed swelling of the first web space in the left hand. Magnetic resonance imaging (MRI) of the left hand demonstrated increased signal on fat-suppressed T2-weighted imaging in the left adductor pollicis. A muscle biopsy specimen demonstrated perimysial and endomysial infiltration of mononuclear cells and eosinophils, and necrosis and regeneration of muscle fibres. Chest computed tomography (CT) revealed upper-lobedominant ground-glass opacities (GGO). Both focal myositis and pulmonary lesions improved without treatment. This case suggests that FEM could involve adductor pollicis and have pulmonary lesions. In this case, myositis and GGO resolved spontaneously. Some FEM cases treated with glucocorticoids were reported in the past. Further studies are required to determine whether patients with FEM require therapeutic intervention.
机译:嗜曙红肌炎的特点是外周血嗜酸性粒细胞和嗜酸性粒细胞渗透在肌肉,由三人亚型:焦嗜酸性肌炎(FEM),嗜酸性多肌炎和嗜酸性perimyositis。通常局限于小腿和肺并发症尚未报道。有限元法在左收肌全身的罕见情况复杂的肺部病变。第一网络空间的膨胀发展左手。左手显示增加的信号fat-suppressed t2加权成像在左边内收肌全身。perimysial和endomysial单核细胞浸润嗜酸性粒细胞,坏死和再生肌肉纤维。揭示upper-lobedominant毛玻璃混浊(GGO)。没有治疗肺部病变改善。这种情况下表明有限元可能涉及全身和肺内病变。这种情况下,肌炎和GGO解决自发。糖皮质激素被报道在过去。还需要进一步的研究来确定有限元的患者需要治疗干预。

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