PEG SUPPORTED PROLINE AS A LIQUID-LIQUID BIPHASIC CATALYST IN KNOEVENAGEL CONDENSATION REACTIONS

摘要

Proline, generally used as a base catalyst for organic reactions, was modified by supporting on PEG (polyethylene glycol) and used as an acid catalyst. The supported material was applied as a nonaqueous biphasic catalytic system in the Knoevenagel condensation for the synthesis of α, β-unsaturated compounds under mild reaction conditions and the proposed mechanism was supported by kinetic studies. After completion of the reaction, the catalyst could be separated and reused by selective product extraction. The catalyst was characterized by techniques such as FT-IR, NMR, CHN, and TGA-DSC analysis.